Retrospective
Analysis of Epidemiological Profile of Hypertensive Patients
John Masih1*, Bansal A.2, Thakur Amit K.1 and Painkara
U.S.3
1Assistant Professor, Medicine, Govt. Medical College, Jagdalpur
2Associate Professor, O.B.G., Govt. Medical College, Jagdalpur 3Professor &H.O.D., Medicine,
Govt. Medical College, Jagdalpur
ABSTRACT:
Back Ground :Countless actors have hammed death by
clutching their heart in imagined pain before collapsing ,yet this Bollywood over kill has had no effect on most Indians, who
remain oblivious to the threat of cardiovascular disease (heart attack and
stroke)till it comes knocking on their doors.
Material and method: The study is retrospective in nature and
was conducted in a tertiary care hospital. The data was collected in a pre
drawn and pre tested proforma between May 2003 and
May 2004.
Variables: Age, gender, Nature of diet, Obesity, Family
history, Smoking, Alcoholism etc.
Observations and Discussion: More than fifty percent patients were either
normotensive or in pre hypertensive stage.18 % and 29
% were in hypertension stage-I, II and III. There were only five patients who
gave history of hypertension running in their families.45 % were hypertensive
obese out of these 67.85 % were suffering from Diabetes. 52.72 % smokers were
found hypertensive.
Conclusion and Recommendations: Modifiable factors played an important
role in causing hypertension along with some biological factors like obesity,
diabetes etc. The impact of these factors can be minimized by changing their
life style like spend at least 30 minutes in exercise every day, reduce their
body weight etc.
KEY-WORDS:
Life style, Waistlines
INTRODUCTION:
Indian Heart Watch data (1-2) reveals that one in two
Indian smoker's don’t know that their tobacco addiction causes stroke while
385-more than one in three- don’t knows
it causes heart disease. While people in smaller cities smoked and ate more
fatty food and less fresh fruits and vegetables, metro-residents tend to be
less active. Obesity, high blood pressure and high cholesterol were uniformly
high, with people doing little to lower their risk. The data further reveals
that even among literate middle-class urban Indians, awareness and control
rates of risk factors was low, for example, roughly one in three people
surveyed had hypertension ,of which only 575knew they had high blood pressure.
Among those with diagnosed hypertension, 40% were on medicine to lower it but
25%had it under control. In comparison ,high income countries ,60 % people with
diagnosed high blood pressure have it controlled, reported researchers at the
World Congress of Cardiology. Roughly half of all heart attacks and strokes
come out of the blue in people with no diagnosed heart disease, so identifying
risk factors early in healthy people is a must to delay disease and prevent
death. By keeping in mind the above facts and as per recommendations of the
World Health Organization (W.H.O.) study group in 1957, that in order to get a
comprehensive picture of a disease, more and more such studies have to be
carried out, Garg Narendra
K.(3) and Garg Narendra K.
and Sharma A.B.(4), the authors have under taken this study with the objective
to study the epidemiological profile of Hypertensive patients retrospectively.
MATERIAL
AND METHODS:
The study is retrospective in nature and was conducted
in a tertiary care hospital, Raipur (C.G.).The data was collected in a pre
drawn and pre tested Performa between May 2003 and May 2004.Variables used were Age, gender, Nature of diet,
Obesity, Family history, Smoking, Alcoholism etc.
Hypertension: Hypertension is defined as sustained
increase in systolic BP of 140mm Hg or more and diastolic BP 90mmHg or more.
Classification of Blood
Pressure for adults , JNC -VII guide line post graduate Medicine , 2004(5).
|
JNC7BP categories |
JNC6BP categories |
SBP mm of Hg |
And /or |
DBP mm of Hg |
|
Normal |
-- |
<120 |
And |
<80 |
|
Pre Hypertension |
Optimal |
120 – 139 |
Or |
80-89 |
|
|
Normal |
<130 |
And |
<85 |
|
|
High Normal |
130-139 |
Or |
85-89 |
|
Hypertension |
Hypertension |
-- |
---- |
---- |
|
Stage -I |
Stage –I |
140-159 |
Or |
90-99 |
|
Stage –II |
-- |
> 160 |
Or |
> 100 |
|
-- |
Stage –II |
160-179 |
Or |
100-109 |
|
-- |
Stage –III |
> 180 |
Or |
> 110 |
OBSERVATIONS
AND DISCUSSION:
On analysis of the collected data it was noted that as age
advances B.P.goes up in both sexes except in 71
+years of age group. Highest number of patients were in pre-hypertensive stage
(Table-I). It was further observed that number of males were more in each stage
of hypertension. In the present study there were only 11 % patients were
vegetarian rest 89 %non vegetarian (Table-II).Highest number of patients were
in pre hypertensive stage. It has been further noted that in both vegetarian
and non vegetarian, in each stage number of males were more than their counterparts
females.
Higher number of obese patients without diabetes were
in normotensive stage in comparison to their
counterparts obese with diabetes while in pre-hypertensive and stage-I, almost
equal number of patients were found both in obese with diabetes or without
diabetes (Table-III).In stage –II&III there were higher number of obese
patients were found with diabetes in comparison to nine diabetics obese. It
shows that obesity plays an important role in causing hypertension. .There were
higher number of males in Stage I to III of BP with Diabetes in comparison to
females (Table-IV) in almost all age groups. In normotensive
stage there were only seven and two diabetic male and female respectively .In prehypertensive stage there were no person was noted
irrespective of gender while in age group from 41 and above years of age there
were eighteen and six male and females diabetics respectively There were only
one female smokers (Table-V). It was further noted that she belongs to
hypertensive II&III stage. While out of two non smokers females one each in
stage –I and stage-II&III of blood pressure. Seventeen and nine male
smokers and non smokers respectively were in Sage –I and Stage –II &III
stage of Blood Pressure. Again table further reveal that there were nineteen
males smokers and non smokers fall in pre hypertensive stage of BP against
three and four smoker and non smokers
males respectively in normotensive stage.
These higher number of hypertensives indicate that
smoking has positive impact on Blood Pressure.
There is now stastical proof
that urban Indian life styles are queering the pitch for the Indian heart (6)
Blood pressure might be dipping across the world but in India ,it has risen.
The W.H.O.says the average BP went down by 2.7mm
mercury among women globally, while increasing by 2.4 mm mercury in India. In
men, it decreased by 2.3 mm mercury globally in the past three decades but in
India it went up by 2.2 mm mercury (6). Nearky 139
million Indians were suffering from high BP at the end of 2008-14 % of the
global burden of uncontrolled hypertension.
The study by the Harvard School of Medicine found that
screening an additional 25 % of the population would lead to an increase of
more than 10 % in the rate of appropriate treatment of hypertension in
high-risk individuals (6).High BP is the leading risk factor for cardiovascular
disease mortality, causing more than 7 million deaths every year worldwide. The
Havard study presented at the world congress of
Cardiology in Dubai says 900 million people in developing countries have high
BP but only one third are aware of their disease. Moreover, only 100 million of
these people receive treatment, while only 5 % of the total are controlled. Dr.
Ashok Seth, chairmen of Escorts heart I institute said,' over 50 % people in
India don’t know they have high BP till incidentally found on a routine health
checkup. The danger is that in many, it presents in the form severe high
pressure called hypertensive crisis which lead to temporary stroke, bleeding in
eyes and heart failure. Those with high risk like family history of high BP and
heart disease and smokers should get their BP checked at regular
intervals". Dr. Deepak Natrajan, head of
interventional cardiology at Moolchan hospital told
TOI," very young people are now coming to us with a full blown heart
attack and one of the reasons for this is uncontrolled high BP .Youngesters today have very poor life style triggered by
their extremely busy schedules".
India is seeing a massive increase in BP levels which
is a huge contributor to stroke and heart attacks. Youngesters
must spend at least 30 minutes excersing every day,
consume a good amount of fruit and vegetables and reduce their body weight (6).
Mothers who are exclusively breastfeeding their babies
for at least six months can lower their risk of developing high BP later in
life by a quarter. Researchers in the university of North Carolina in the U.S.
found that women who gave their babies formula or breast fed for less than three
months were almost a quarter more likely to develop blood pressure problems. In
the study there were 56,000 mothers with at least on child concluded that
mothers who breast fed for at least six months were less likely to develop
hypertension over 14 years period than those who bottle fed. The research
further observed that up to 12%of high BP cases among women with children could
be linked to "suboptimal" breast feeding. While the findings do not
prove breastfeeding was behind healthier blood pressure ,the researchers said
it added to evidence that it was good for both mothers and babies(7), published
in the American J of Epidemiology.
There could soon be a cap on how much salt is put in
your fries. Raising taxes on products containing salt would reduce the
incidence of stroke by 4% and heart attack by 2% in India. Salt is known to
cause high blood pressure or hypertension that is responsible for 57% of deaths
due to stroke and 24% of mortality by heart attack in India (8). Sodium makes
blood vessels less able to contract or expand and may toughen heart cells.W.H.O. says an adult should not consume more than
5gm.of salt a day. However, an Indian consume double the prescribed
limiti.e.10gm a day. Dr. K Srinath Reddy, president
of the world heart federation ,said" people will have to b educated on
reducing salt use while cooking, beside giving up the habit of adding table
salt in their foods. He further added that we also will have to be ensure that
processed foods don't contain high salt levels". The Harvard study found
that a salt tax would save money by reducing the number of people needing
treatment for hypertension and CVD events such as heart attacks and
stroke.
TABLE-I: Hypertensive as per
age and gender (n=64)
|
HYPERTENSION |
Age in years and
gender |
Total |
|||||||||
|
31-40 |
41-50 |
51-60 |
61-70 |
71and above |
|||||||
|
M |
F |
M |
F |
M |
F |
M |
F |
M |
F |
|
|
|
Normotensive (<120/<80) |
05 |
01 |
03 |
01 |
04 |
02 |
01 |
01 |
00 |
01 |
19 |
|
Pre- Hypertensive
(120-139/80-89) |
04 |
01 |
03 |
04 |
12 |
02 |
06 |
01 |
05 |
00 |
38 |
|
Stage -I
Hypertension (140-159/90-99) |
01 |
00 |
04 |
01 |
05 |
03 |
01 |
01 |
01 |
00 |
17 |
|
Stage -II &
III Hypertension (>160/>100) |
01 |
01 |
04 |
01 |
06 |
03 |
03 |
01 |
04 |
02 |
26 |
|
Total |
11 |
03 |
14 |
07 |
27 |
10 |
11 |
04 |
10 |
03 |
100 |
TABLE-II: Hypertensive as per
their Diet
|
|
Normotensive (<120/<80) |
Pre- Hypertensive
(120-139/80-89) |
Stage -I
Hypertension (140-159/90-99) |
Stage -II &
III Hypertension (>160/>100) |
Total |
|||||
|
Gender |
M |
F |
M |
F |
M |
F |
M |
F |
|
|
|
Diet |
Vegetarian n=11 |
01 |
01 |
03 |
00 |
03 |
00 |
02 |
01 |
11 |
|
Non-Vegetarian
n=89 |
12 |
05 |
27 |
08 |
09 |
05 |
16 |
07 |
89 |
|
|
Total |
13 |
06 |
30 |
08 |
12 |
05 |
18 |
08 |
100 |
|
TABLE-III: Hypertensive as per
their obesity (n=62)
|
|
Normotensive (<120/<80) |
Pre- Hypertensive
(120-139/80-89) |
Stage -I
Hypertension (140-159/90-99) |
Stage -II &
III Hypertension (>160/>100) |
Total |
|||||
|
Gender |
M |
F |
M |
F |
M |
F |
M |
F |
|
|
|
Obese |
Obese with
Diabetes n=35 |
02 |
02 |
11 |
01 |
02 |
02 |
12 |
03 |
35 |
|
Obese with
out-diabetes n=27 |
03 |
04 |
07 |
04 |
04 |
01 |
03 |
01 |
27 |
|
|
Total |
05 |
06 |
18 |
05 |
06 |
03 |
15 |
04 |
62 |
|
TABLE-IV: Distribution of
Diabetic Hypertensive as per their age and gender (n=50)
|
Stages of Blood Pressure |
HYPERTENSION WITH DIABETES |
Total |
|||||||||
|
31-40 |
41-50 |
51-60 |
61-70 |
71and above |
|||||||
|
M |
F |
M |
F |
M |
F |
M |
F |
M |
F |
|
|
|
Normotensive (<120/<80) |
03 |
00 |
02 |
01 |
02 |
01 |
00 |
00 |
00 |
00 |
|
|
Pre- Hypertensive
(120-139/80-89 |
00 |
00 |
03 |
01 |
07 |
03 |
06 |
01 |
02 |
01 |
|
|
Stage -I
Hypertension (140-159/90-99 |
02 |
00 |
01 |
01 |
02 |
00 |
00 |
01 |
00 |
00 |
|
|
Stage -II &
III Hypertension (>160/>100) |
01 |
00 |
01 |
02 |
01 |
01 |
02 |
02 |
00 |
00 |
|
|
Total |
06 |
00 |
07 |
05 |
12 |
05 |
08 |
04 |
02 |
01 |
|
TABLE-V: Hypertensive as per
their Smoking Habit (n=55)
|
Smoking Habit |
Normotensive (<120/<80) |
Pre- Hypertensive
(120-139/80-89 |
Stage -I
Hypertension (140-159/90-99 |
Stage -II &
III Hypertension (>160/>100) |
Total |
||||
|
M |
F |
M |
F |
M |
F |
M |
F |
|
|
|
Smoker n=32 |
03 |
00 |
11 |
00 |
06 |
00 |
11 |
01 |
32 |
|
Non-Smoker n=23 |
04 |
00 |
08 |
00 |
04 |
01 |
05 |
01 |
23 |
|
Total |
07 |
00 |
19 |
00 |
10 |
01 |
16 |
02 |
55 |
REFERENCES:
(1). Sanchita Sharma ;Ticker Trouble : Sunday Hindustan Times,
New Delhi, May 20,2012 :pp-18.
(2). Turning fat in
many ways ;Sunday Hindustan Times, New Delhi, December 04,2011;pp-16
(3).Garg Narendra K.: Evaluation of
the impact of emesis and emesis plus purgation Therapy; Research J Pharmacology
and Pharmacodynamics:2 (2) March-April;2010:201-202.
(4).Garg Narendra K and Sharma A.B. :
Epidemiological profile of patients attending a tertiary care hospital, Muktsar, Punjab (India); Research J Pharmacology and
Pharmacodynamics:3 (6) November-December;2011:311-317
(5).JNC 7
guidelines and Indian scenario chapter 17, Apicon
postgraduate Medicine: Vol.18 :2004.
(6) We have weaker hearts than
Americans : Study; Sunday Times of India ,New Delhi, April 22,2012 : pp15
(7).Breastfeeding cuts Blood Pressure
risk in women : The Times of India ,New Delhi, December 28,2011; pp13.
(8).Study moots salt tax to
lower risk of stroke : Sunday Times of India ,New Delhi, April 22,2012 : pp15
Received on 23.08.2012
Modified on 10.10.2012
Accepted on 16.11.2012
© A&V Publication all right
reserved
Research J. Pharmacology and
Pharmacodynamics. 5(2): March –April 2013, 106-109